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Aldehyde dehydrogenase (NAD(P)+) : ウィキペディア英語版 | Aldehyde dehydrogenase (NAD(P)+)
In enzymology, an aldehyde dehydrogenase () () is an enzyme that catalyzes the chemical reaction :an aldehyde + NAD(P)+ + H2O an acid + NAD(P)H + H+ The 4 substrates of this enzyme are aldehyde, NAD+, NADP+, and H2O, whereas its 4 products are acid, NADH, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is aldehyde:NAD(P)+ oxidoreductase. Other names in common use include aldehyde dehydrogenase (), and ALDH. This enzyme participates in 5 metabolic pathways: glycolysis / gluconeogenesis, histidine metabolism, tyrosine metabolism, phenylalanine metabolism, and metabolism of xenobiotics by cytochrome p450. ==Structural studies==
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes , , , and .
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